Great simplification pulsing lines

Ep 117  |  Geoffrey West

Geoffrey West: “Metabolism and the Hidden Laws of Biology”

Check out this podcast

TGS117 Geoffrey West The Great Simplification

Show Summary

On this episode, physicist Geoffrey West joins Nate to discuss his decades of work on metabolic scaling laws found in nature and how they apply to humans and our economies. As we think about the past and future of societies, there are patterns that emerge independently across cultures in terms of resource use and social phenomena as the size of a city grows. Does Kleiber’s law, which describes the increasingly efficient use of energy as an animal gets larger – also apply to human cities? How have humans deviated from this rule through excess social consumption beyond a human body’s individual metabolic needs? What could we learn from these scaling laws to adjust our communities to be more aligned with the biophysical realities of energy and resource consumption? Can an understanding of social metabolism impact our social metabolism?

About Geoffrey West

Geoffrey West is the Shannan Distinguished Professor and former President of the Santa Fe Institute and an Associate Senior Fellow of Oxford University’s Green-Templeton College. West is a theoretical physicist whose primary interests have been in fundamental questions ranging across physics, biology and the social sciences. His work is motivated by the search for unifying principles and the “simplicity underlying complexity”. His research includes metabolism, growth, aging & death, sleep, cancer, ecosystems, innovation and the accelerating pace of life. Most recently he has been developing a science of cities and companies, including the challenge of long-term global sustainability of the anthroposphere. He is the author of the best-selling book Scale; The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies.

Show Notes & Links to Learn More

Download transcript

00:00 – Geoffrey West works + info, Scale; The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies,

00:59 – Kleiber’s Law

03:30 – Max Kleiber

05:35 – Logarithmic scale

08:02 – Newton’s Laws

10:51 – ~100 trillion cells inside humans

12:55 – Keiber’s law and forests

14:01 – Energy requirements of ‘the internet’

14:17 – Anthroposphere

16:55 – Exosomatic metabolic rate

17:38 – The Blue Whale is the biggest animal to ever exist

23:01 – Urban Superlinearly Scaling of social metabolism

25:39 – Howard T. Odum, Maximum Power Principle

28:40 – Urban Sublinear Scaling of Infrastructure

29:45 – Dopamine

30:31 – Complexity of the human metabolism

31:15 – New York population and patents vs Santa Fe population and patents

32:26 – Economics for the future – Beyond the superorganism

32:44 – Ronald Wright, Marco Polo, Hernán Cortés

35:45 – Eusocial

39:54 – Degrowth

41:25 – Superlinear social scaling requires the constant speeding up the pace of life

43:55 – Jesus Christ, Mahatma Gandhi, Martin Luther King Jr.

52:32 – Open and Closed Systems

55:23 – Developed countries are 80% urbanized

58:35 – 15 minutes city

1:01:33 – E.O. Wilson

1:02:49 – 80/20 Rule

1:16:57 – Pre-Colombian cities followed these scaling laws

1:17:25 – Resource use through the rise and fall of Rome

1:18:02 – Metabolism of companies

1:21:40 – Why do humans live as long as they do

1:27:33 – Reducing your metabolism would increase your life (fasting)

1:39:20 – Why We Die

Back to all posts
Saving Bats to Save OurselvesWith Iroro TanshiThe Great SimplificationEp 241 | Iroro Tanshi

In this episode, Nate is joined by Nigerian bat biologist Iroro Tanshi to explore how the rediscovery of a bat species unseen in Nigeria for 45 years – and a wildfire that destroyed half its habitat just days later – launched a community-led fire prevention program. Iroro explains how listening to farmers, who no longer knew when it was safe to burn their fields, led to a simple fire danger warning system that local leaders then backed with their own bylaws, directly addressing tragedy-of-the-commons dynamics. She also shares what it’s like to navigate conversations about climate and biodiversity with rural Nigerian communities, and how her team is now scaling their fire management solution across the tropics.

Watch nowNov 4, 2026
A Shattered Market?With Rory JohnstonThe Great SimplificationEp 240 | Rory Johnston

In this episode, Nate welcomes back oil market analyst Rory Johnston for an update on how the crisis has evolved since April. Rory explains why diesel is now the epicenter of the crisis, with crack spreads running five to six times their historical norm, driven by both the Iran war and Ukraine’s strikes on Russian refineries. He also unpacks one of the unexpected moves that lessened the severity of the energy shortage: China’s unprecedented 45% cut in crude imports, which he calls the “Beijing Swing.” Tying these trends together, Rory and Nate explore how soaring shipping costs have fractured a once-global oil market into regional pockets and how the poorest nations are bearing the brunt of demand destruction.

Watch nowOct 28, 2026
Earth's Oldest TeachersWith Robin Wall KimmererThe Great SimplificationEp 239 | Robin Wall Kimmerer

In this episode, Nate is joined by Robin Wall Kimmerer to explore what we can learn from some of Earth’s oldest and smallest beings: plants. Robin weaves together her experience as a botanist and a Citizen Potawatomi Nation member to offer what she’s learned about living well within nature’s limits, including practices such as the Honorable Harvest and the importance of restraint and reciprocity. She also shares the Potawatomi prophecy of the Seventh Fire, in which humanity stands at a fork between a scorched path and a green one, and can only move forward by walking back to recover what was lost along the way. Robin frames this moment as the age of remembering – an invitation to restore the land and our relationship with it.

Watch nowOct 21, 2026

Subscribe to our Substack

The Institute for the Study of Energy and Our Future (ISEOF) is a 501(c)(3) non-profit corporation, founded in 2008, that conducts research and educates the public about energy issues and their impact on society.

Support our work
Get in touch
x