Ep 206 | Anna Lembke
How We’ve ‘Drugified’ Our Entire Existence: Dopamine & Addiction In the Digital Age
Description
Dopamine: the most famous neurotransmitter that regulates pleasure, motivation, and (perhaps most importantly) addiction. When examining why our society is hooked on consuming more and more of everything – food, clothes, videos, news, vacations – it’s imperative to look at how our modern environments hijack our brain’s dopamine, sending it into overdrive at nearly every turn. Could taking a closer look at how our societal norms make us more vulnerable to addiction help us transition to more balanced and mindful lifestyles?
In this episode, Nate is joined by New York Times bestselling author and professor of psychiatry, Anna Lembke, to explore how modern society has “drugified” our lived experience through digital media, processed foods, and instant gratification, resulting in an environment that propagates addiction. She explains how dopamine works as our brain’s reward signal and why our ancient wiring is mismatched for today’s level of high-dopamine stimuli in everyday life – leading to tolerance, withdrawal, and even anhedonia. Ultimately, Anna emphasizes that addiction is not a personal failing but a predictable response to an environment designed to take advantage of our brain’s neurochemistry.
What are the key practices individuals can use to reduce their addictive tendencies, even as our culture continues to prioritize quick dopamine hits and consumption? How long does it take to see the positive effects after moving away from the stimulus related to our addictive behavior? Lastly, if we acknowledge that information alone isn’t enough, what cultural shifts can we make to foster more connection, digital mindfulness, and authenticity, in order to return to a slower, lower throughput way of living?
About Anna Lembke
Anna Lembke is professor of psychiatry at Stanford University School of Medicine and chief of the Stanford Addiction Medicine Dual Diagnosis Clinic. As a clinician scholar, she has published more than a hundred peer-reviewed papers, book chapters, and commentaries. She sits on the board of several state and national addiction-focused organizations, has testified before various committees in the United States House of Representatives and Senate, and maintains a thriving clinical practice.
In 2016, she published Drug Dealer, MD – How Doctors Were Duped, Patients Got Hooked, and Why It’s So Hard to Stop, which was highlighted in the New York Times as one of the top five books to read to understand the opioid epidemic. Dr. Lembke also appeared on the Netflix documentary The Social Dilemma, an unvarnished look at the impact of social media on our lives.
Her most recent book, Dopamine Nation: Finding Balance in the Age of Indulgence, explores how to moderate compulsive overconsumption in a dopamine-overloaded world and is a New York Times Bestseller.
In French, we have a motto that says that a simple drawing is often better than a long explanation. Jean-Marc Jancovici Carbone 4 President
That’s very understandable because with left atmosphere thinking, one of the problems is that you see everything as a series of problems that must have solutions. Iain McGilchrist Neuroscientist and Philosopher
We can’t have hundreds and hundreds of real relationships that are healthy because that requires time and effort and full attention and awareness of being in real relationship and conversation with the other human. Nate Hagens Director of ISEOF
This is the crux of the whole problem. Individual parts of nature are more valuable than the biocomplexity of nature. Thomas Crowther Founder Restor
Show Notes & Links to Learn More
Download transcriptThe TGS team puts together these brief references and show notes for the learning and convenience of our listeners. However, most of the points made in episodes hold more nuance than one link can address, and we encourage you to dig deeper into any of these topics and come to your own informed conclusions.
00:00 – Anna Lembke: Bio + Works
05:05 – Digital media, drugs, and alcohol trigger same reward pathways in the brain
06:58 – Wolfram Schultz, paper on rewards and dopamine neurons in monkeys
07:09 – Peter Whybrow – American Mania: When More is Not Enough, TGS Episode
10:57 – Dopamine, serotonin, oxytocin, norepinephrine
12:16 – Experiment: probe in nucleus accumbens in rat brain measures dopamine firing increase in response to chocolate (55%), sex (100%), nicotine (150%), cocaine (200%), amphetamine (1000%)
15:30 – Dopamine addiction and fasting
23:10 – Phenomenology, phenomenological approach to addiction
23:24 – Addiction is a spectrum
25:10 – 10-15% U.S. alcohol use disorder prevalence, ~10% U.S. drug use disorder prevalence
29:02 – Factors that increase risk of addiction
31:25 – The Great Simplification movie
32:27 – Heads of AI labs publicly warning that these models might cause human extinction, Geoffrey Hinton (“Godfather of AI”) warnings about ASI
32:42 – The Social Dilemma, Tristan Harris + TGS Episode
36:06 – Jonathan Haidt, Jonathan Haidt on TGS
36:25 – Porn addiction and impact on real-life relationships
37:20 – Anhedonia
38:48 – DSM-5 Diagnostic Criteria: Substance Use Disorder
46:57 – How long does detox take?, Protracted abstinence, Neuroplasticity
47:56 – Nora Volkow on methamphetamine addiction and dopamine transmission
48:30 – Addiction and genetics, Family and twin studies regarding lived environment and genetic factors in addiction
55:03 – Adolescence and addiction, Seniors and addiction
56:17 – Neuroplasticity as we age
56:38 – Frankly #112: The Quadruple Bifurcation
1:03:11 – Carbon pulse
1:03:56 – In the U.S. more people are living alone than ever before
1:04:39 – Isolation in retirement communities
1:06:22 – Derealization, depersonalization
1:18:13 – Radical honesty, Anna Lembke video on radical honesty and addition
1:21:30 – Most adults tell 1-2 lies per day
1:24:05 – Anna Lembke on Diary of a CEO
1:27:15 – Internet and Technology Addicts Anonymous
1:27:44 – GLP-1s and dopamine, Opioid antagonists (receptor blockers)
1:29:24 – Audrey Tang + TGS Episode



